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IGF-1 LR3 also promotes muscle cell proliferation and differentiation through activation of satellite cells, the resident stem cells of skeletal muscle
doi: 10.1007/s13669-024-00398-7
10.1016/j.isci.2023.106057 Summary Keywords drug mechanism, metformin, type 2 diabetes, gastrointestinal tract, gut microbiota Citation Cheng M, Ren L, Jia X, Wang J and Cong B (2024) Understanding the action mechanisms of metformin in the gastrointestinal tract
Reported activities include fibroblast stimulation, controlled intracellular copper delivery, modulation of collagen and glycosaminoglycan synthesis, and broad changes in gene expression across stress-response and tissue-repair networks
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The results of a prior study confirmed the protective benefits of L-carnitine due to suppression of inflammation, oxidative stress, and increased autophagy (Khedr and Werida 2022)
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