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These include how bad the B12 deficiency is, any health issues, and how well the body responds to the treatment

[14] [15] Patients with significant anaemia require monitoring of serum potassium, particularly during loading doses

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Dietary deficiency: Strict vegans or very poor diets may lack animal-source B12

For the vitamin to serve inside cells, the TC2-B 12 complex must bind to a cell receptor protein and be endocytosed