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Clinical studies show that kojic acid can reduce melanin synthesis by up to 80%, which translates to visible lightening of dark spots and overall skin tone
10.1155/2020/6183757 J
large thiamine doses can cause severe allergic reactions
The origin of cytosolic NADH is from the pathway of glycolysis and the electrons in cytosolic NADH are transported into the mitochondria via the actions of the malate-aspartate shuttle (to mitochondrial NADH) or by the glycerol phosphate shuttle (to mitochondrial FADH 2 )
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& Jacquot, J
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