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Potential Benefits of Micro-Dosing GLP-1s: Sustained Appetite Control : Even at lower doses, GLP-1s can continue to help regulate appetite and prevent overeating, making it easier to maintain weight loss over the long term
touchREV Endocrinol 2024;20:7280
Cardiovascular Benefits Large clinical trials show that certain GLP-1 medications: Reduce major cardiovascular events Improve blood pressure and cholesterol Support overall heart health in high-risk patients This makes them especially valuable for patients with diabetes and cardiovascular risk factors
10.1042/CS19980050
Tesamorelin is a good example: FDA labelling reports 8 minutes in healthy subjects after a single subcutaneous dose, while other reported figures come from different populations and dosing schedules
This is also seen for the weight loss, where the differences are rather small in the combination therapy arms of the study, as these seem to have reached maximal weight loss, albeit the lack of a lean control group confounds this conclusion
