Some research suggests combining them may have additive effects, but most athletes get better results from L-citrulline alone
But heart palpitations arent typically one of them
The rationale is to prevent potential receptor desensitization, though clinical evidence for this is limited
In the MD studies, weaker interactions of oxyntomodulin with residues deep in the cavity, particularly R190 2.60 , were coupled with a loss of stable interactions along the entire face of the TM2 helix and weaker interactions with ECL2, all of which interact with the same face of the helical GLP-1 peptide (Fig
More concerning side effects include persistent fatigue and hair loss that some users experience on higher doses
WeightWatchers centers on habit change, accountability, and community support while offering access to GLP-1s