[4] [8] Some patients may also experience diarrhoea, and bowel habits can fluctuate during treatment
[1] Body weight and composition can influence the volume of distribution for GLP-1 medications, potentially affecting elimination kinetics
Based on these criteria, Novo Nordisk estimates that approximately 10% of people with obesity would meet the indication
Common Side Effects Nausea Vomiting Diarrhea Stomach pain Decreased appetite Serious Side Effects Pancreatitis (severe stomach pain, nausea) Gallbladder issues (gallstones, pain in the upper abdomen) Thyroid tumors (seen in animal studies) Some patients also report feeling still hungry on semaglutide, which may be related to how their body responds to the medicationor differences in dosage or absorption
989-1002, Duncan, Jessica, et al
Retatrutide NAFLD - Phase 2 Trial Results in Subset of Patients with Obesity and NAFLD