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The contributions of GIP and glucagon receptor activation to bowel changes are not yet well characterised for retatrutide specifically, and any claims about their effects on gut motility or intestinal secretion remain uncertain given the medicine's investigational status
It is high in calories, which can slow weight loss progress, and it may worsen side effects like nausea or diarrhea
But for most people, what you want to do is take 30 grams of protein and have that four times a day
doi: 10.1111/dom.14255, 54 GrahamD
doi: 10.3389/fmed.2020.00458 3 AydemirD.UlusuN
For weight management, the FDA-approved options are Wegovy (semaglutide), Zepbound (tirzepatide), and Foundayo (orforglipron)
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