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Some compounding protocols allow limited room-temperature stability (up to 8 hours for certain formulations), but extended storage outside refrigeration creates unpredictable potency loss

For patients with severe obesity (BMI 40 kg/m or 35 kg/m with comorbidities) who have not achieved adequate weight loss with non-surgical interventions, bariatric surgery may be considered following specialist assessment, as outlined in NICE CG189

"Extreme side effects, they told me, were not unusual

John Diaz

Physical sensations during injection often provide the first clue

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