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These findings highlight a pivotal regulatory role for dopamine in iron deposition, which may be directly relevant to the iron overload and subsequent ferroptosis in SNpc dopaminergic neurons

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The Journal of Clinical Investigation

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Whether this observation is solely the consequence of translocation of Parasutterella bacteria from the intestine to the EWAT or driven by more indirect mechanisms such as bacterially-produced metabolites 85 is yet to be determined

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