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Human clinical trial data remains limited, with Phase I and II trials for inflammatory bowel disease conducted in the 1990s claiming safety with no toxicity, though full peer-reviewed data never appeared in scientific literature

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The study used three conditions: fasting, a high carbohydrate meal (85% of energy from carbs), and a high protein meal (94% of energy from protein)

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For these reasons, professional oversight is necessary to navigate the lack of standardized human dosing and to ensure the purity of the source

By getting a B-12 shot you can bypass the stomach entirely and it can be absorbed directly into the bloodstream