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These effects are mediated through binding of calcitonin to a specific receptor (the calcitonin receptor or CTR) on the osteoclast (20), a specialized cell that resorbs bone, causing it to retract and cease bone resorption (21)

If youve been prescribed a weight loss medication or have been reading up on oral GLP-1s, you may be wondering how these options differ from the long-used injections

It requires philanthropic, academic, or government-funded trials, which is a tractable problem rather than a sinister one

10.1001/jamanetworkopen.2023.14493 73 ShahwarD.BaqaiS.KhanF.KhanM

After starting a weekly Zepbound regimen last year, Putur said, she has lost 80 pounds and feels more energized