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As of mid-2026, neither compound is approved by the FDA or the EMA for any indication , so no established or approved human dose exists for either, and anything sold under those names outside a monitored trial is a research-use-only chemical of unverified identity

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A key selectivity advantage is attributed to ipamorelin: in the original characterization studies it stimulated GH strongly while showing minimal effect on adrenocorticotropic hormone (ACTH), cortisol, and prolactin hormones that older GHRPs such as GHRP-6 tended to elevate

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