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Exclusion criteria: Non-RCTs (cohort, casecontrol, cross-sectional studies, case reports)

What are side effects of GLP-1 medications

Aripiprazole caused initially fatigue, muscular spasms of jaw, and slurring of speech at the dose of 5 mg/day

Later, patients using these drugs reported unexpected weight loss due to reduced appetite, which shifted their use from diabetes treatment to mainstream weight-management therapy