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Experimental models show that Exenatide reduces hippocampal gliosis, improves serotonergic and GABAergic signaling, and alleviates behavioral disturbances, suggesting a pathway targeting inflammation, oxidative stress, and neurotransmitter imbalances [27]

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Most common side effects are nausea, jaw ache, and depression

doi:10.3389/fphys.2022.960580

These are systemic effects that berberine also touches through its own mechanisms, which creates both complementarity and the need for careful management

The link between periodontal disease and rheumatoid arthritis: an updated review