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the crude HR for hip fracture with GLP-1 RAs compared to DPP-4is was 0.68 [0.490.96], which was unaltered in the fully adjusted model (HR 0.65 [0.460.93])

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While resmetirom remains the only FDA-approved therapy to date, experimental agents such as elamipretide (SS-31) and uncoupling protein 2 (UCP2) modulators are under investigation to restore mitochondrial integrity and reduce ROS production [103106]

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The GLP-1 RAs group had lower risk of complicated pancreatitis (HR 0.32

The final concentration of HGF in media was set at 5 ng/ml, which has been shown to maximally activate satellite cells in our primary culture system 19