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Some common side effects include headache, blockage of nose, fatigue, and stomach pain

50 Similarly, upregulation of thymidylate synthase (TYMS), a target of 5-fluorouracil (5-FU), contributes to resistance in colorectal cancer by augmenting DNA repair pathways

2007;12 Suppl 1:43-51

If you are correcting a deficiency, the first few injections are usually spaced close together to rebuild your stores, then moved to a maintenance schedule

So, at this scale, drug levels are up at like 25,000