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In various pathological conditions implicating oxidative stress, ER functions are disturbed resulting in ER stress and initiation and propagation of unfolded protein response (UPR), which results in transient suppression of protein translation to allow recovery but leads to cell death when stress cannot be resolved (Soliman et al., 2019)
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An introduction to poliovirus: pathogenesis, vaccination, and the endgame for global eradication
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