CYP1A1 metabolism of estrogen, polyaromatic hydrocarbons, and more CYP1A2 metabolism of caffeine, duloxetine, bupropion, aflatoxin B, and more CYP2A6 metabolism of nicotine, coumarin, and more CYP2B6 metabolism of ketamine, methadone, sertraline, and more CYP2C9 metabolism of warfarin, rosuvastatin, celecoxib, and more CYP2C19 metabolism of clopidogrel, some proton pump inhibitors, more CYP2D6 metabolism of some antidepressants, antipsychotics, more CYP3A4 metabolism of half of all prescription drugs CYP2E1 metabolism of fatty acids, alcohol, and some anesthetics Phase II detoxification genes: UGT, GST, Nrf2 Phase II detoxification involves taking the metabolites of phase I and modifying them to be easily excreted through conjugation with sulfur, glutathione, glucuronic acid, amino acids, or methyl groups
In practice, providers may advise against NAD+ injections in patients with serious underlying medical conditions as a precaution
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Tirzepatide provides the most potent results with generally fewer side effects Semaglutide is a highly effective, more affordable alternative especially when dosing is personalized under medical supervision At Potere Health MD, we help our patients choose the safest and most effective treatment based on their goals and medical history