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After coronary artery ligation in mice, intraperitoneal T4 treatment upregulated cardiac ILK and Akt activity, enhanced early myocyte survival, and improved cardiac function establishing the mechanistic basis for the cardiac and broader tissue-repair claims associated with thymosin beta-4 and its 1723 fragment TB-500

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Current therapeutic uses for CJC-1295 and ipamorelin Like sermorelin, another growth hormone secretagogue, CJC-1295 and ipamorelin are non-FDA-approved medications whose therapeutic uses are entirely off-label

This indicates that while higher doses may have some impact on kidney function, this effect is reversible and does not occur at lower, more commonly used doses

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