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Pierre Hofstee P, Bartho LA, McKeating DR, Radenkovic F, McEnroe G, Fisher JJ, Holland OJ, Vanderlelie JJ, Anthony V, Perkins AV, JSM C
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Repeated freeze-thaw cycling is one of the more common causes of peptide degradation, since the formation and melting of ice crystals can physically disrupt peptide bonds with each cycle
FDAs injectable-route concern highlights limited human safety data, aggregation risk, and peptide-related impurity concerns [8]
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