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To understand mediators of cagrilintide action, we generated a transcriptomics atlas of over 530,000 cells comprising 80 neuronal cell populations across rat, mouse and macaque caudal brainstem, with spatial profiling to map distribution in the rat dorsal vagal complex (DVC)
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The Warburg effect indicates that regardless of the oxygen availability, the metabolic reprogramming in tumor cells will inhibit oxidative phosphorylation of mitochondria, so the utilization of glucose tends to be anaerobic glycolysis, rather than aerobic oxidation, which will lead to the accumulation of lactate [14]
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The duration of the included articles ranged from 5 to 48 weeks, and the sample size ranged from 10 to 148 cases
