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Although this was an unselected sample of participants with respect to mental illness, nearly all participants had clinically significant depressive symptoms and anxiety
This muscle loss can impair metabolic health, reduce physical strength, and accelerate aging processes
[Wadden STEP 3, JAMA 2021] STEP 5 Trial (Nature Medicine 2022) Long-term data: patients maintained an average 15.2% weight loss over 2 years of continuous semaglutide use, with sustained metabolic improvements including reduced HbA1c, blood pressure, and waist circumference
These 3.6 million beneficiaries represent just over a quarter (26%) of the 13.7 million Medicare beneficiaries diagnosed as being overweight or obese in 2020
However, like any medication, it can have side effects, including rashes