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According to the U.K

Yes, vitamin B complex supplements can cause diarrhea and other side effects like weakness, headache, nausea, and tingling sensations in some people

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Monitoring Response to B12 Injection Therapy Checking how well Vitamin B12 injections work involves looking at lab results and how the patient feels

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If you start feeling symptoms of deficiency again, your health changes, or your B12 levels drop, you might need to adjust your schedule