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Under conditions of oxygen-glucose deprivation (OGD), astrocytes have also been observed to undergo abnormal activation, participating in mediating neuronal dysfunction through the secretion of inflammatory components [130]

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Lipid metabolism, insulin resistance (IR), oxidative stress (OS), endoplasmic reticulum stress (ERS), inflammation, fibrosis, autophagy, and apoptosis are some of the pathogenic pathways involved

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