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You're a strong candidate for B12 injections if you experience any of the following: Persistent fatigue that sleep doesn't fix Brain fog, forgetfulness, or trouble concentrating Low mood, anxiety, or stress that feels disproportionate to what's happening Weight gain or difficulty losing weight despite consistent effort Tingling, numbness, or weakness in hands or feet (signs of B12-related neuropathy) Frequent colds, slow healing, or post-COVID fatigue A plant-based, vegetarian, or vegan diet Age 50 or older (B12 absorption naturally declines with age) A history of gastric bypass, Crohn's disease, celiac disease, or chronic acid reflux Long-term use of metformin (for diabetes), proton pump inhibitors (Prilosec, Nexium), or H2 blockers (Pepcid, Zantac) An MTHFR gene variant or known methylation issue A history of B12 deficiency, pernicious anemia, or low folate Hormonal shifts: perimenopause, menopause, postpartum If you fit one or more of these, a vitamin B12 shot is one of the lowest-risk, fastest-acting interventions available
It was approved for medical use in the US in 2017
An imbalance or decline in hormones due to aging, often starting during menopause, can lead to metabolic slowdown, decreased energy, and weight gain
FSAs and HSAs are governed by IRS rules more directly, but plan administrators can still require itemized receipts, prescriptions, and substantiation paperwork before paying out
the comment period closed at the end of June 2026, and it is still a proposal
Use it nightly during heavy training blocks or lean on it when travel throws your routine off completely
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