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It acts in muscle, adipose tissue, and liver to turn on a set of genes essential for fatty acid oxidation, including the fatty acid transporters carnitine acyltransferases 1 and 2, the fatty acylCoA dehydrogenases for short, medium, long, and very long acyl chains, and related enzymes

The Problem:

The impact on glycaemic management is most significant for diabetics (either type 1 or 2) who require insulin given most of the carbohydrates in clear fluids are simple sugars

In addition, the possibility to manipulate SLC25A39 and/or to regulate the amount of GSH that enters mitochondria also offers the opportunity to study the importance of mitochondrial GSH in more detail, especially in mitochondria-rich tissues like liver or kidney

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