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This far exceeds the affinity of many endogenous copper-chelating agents, and it matters because that tight coordination is what allows GHK-Cu to donate copper to cuproenzymes and initiate downstream gene expression cascades
This can be beneficial as well in lowering intraocular pressure in certain types of angle-closure glaucoma (rxlist.com) pilocarpine eye drops (2% or 4%) are given in two doses spaced 15 minutes apart as part of the recommended protocol for the emergency management of angle-closure glaucoma, which also includes administering other agents to decrease intra-occular pressure including (acetazolamide iv & po), topical beta blockers (i.e
Capsules maintain stability for 24 months when stored properly
doi:10.1038/oby.2007.24 106
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