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In one study, irinotecan resistant non-small cell lung cancer (NSCLC) cells had increased oxphos compared to treatment-nave NSCLC cells (Lee et al., 2018)

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Therapeutic strategies Given the role of ferroptosis in the pathogenesis of testicular diseases, ferroptosis is a very promising therapeutic target for treating and preventing male reproductive diseases

There's no standard of care for how to de-escalate therapy, and so different physicians have different experiences and practices, adds Biermann