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Proglucagon , a 160-residue peptide produced by the pancreas -cells and the small intestines K and L cells , undergoes selective posttranslational modifications to produce these essential incretin hormones
Circulation 1989
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Researchers often study it in lab work on Nicotinamide N-Methyltransferase (NNMT)
To do so, consume foods high in methionine
The cardiac benefits of GLP-1 agonists were not anticipated before outcome studies were performed for several reasons: (1) Historical Precedent-past experiences with other diabetes medications that unexpectedly had adverse cardiovascular effects made it less likely for researchers and clinicians to anticipate potential cardiovascular benefits without concrete evidence from large-scale trials
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