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doi: 10.18332/tpc/115062

6.5 Inflammatory and autoimmune disorders Dysregulated immune responses, chronic inflammation, and compromised immunological tolerance are the causes of autoimmune and inflammatory diseases, including multiple sclerosis (MS), rheumatoid arthritis (RA), inflammatory bowel disease (IBD), and systemic lupus erythematosus (SLE)

For humans, self-production of B12 through the intestinal bacteria is theoretically possible, but rarely achieved for health reasons, which is why humans today depend on a dietary intake of B12 in almost all cases

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