Kastenmller are co-inventors (through Duke University/Helmholtz Zentrum Mnchen) on patents on applications of metabolomics in diseases of the central nervous system and hold equity in Chymia LLC and IP in PsyProtix and Atai that are exploring the potential for therapeutic applications targeting mitochondrial metabolism in treatment-resistant depression
doi:10.2174/1381612826666200424180139 Park JM, Lee HJ, Sikiric P, Hahm KB
Alzheimers Dement 15, 106152
Who Is a Candidate, and Who Should Wait NAD+ and peptide therapies tend to appeal to generally healthy adults working toward specific wellness goals
Implications Amylin is centrally implicated in metabolic disease: dysregulated synthesis, impaired pro-IAPP processing and aggregation of amylin into islet amyloid are associated with -cell dysfunction and the progressive loss of -cell mass in type 2 diabetes (T2D)
Not only is it important to know all the beneficial effects, but it also is important to know the potential negative effects, so patients can be counseled properly. The next steps would be to design a study to see the mechanism for improvement in cardiovascular health, he added