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Godwin LS, Castle JT, Kohli JS, Goff PS, Cairney CJ, Keith WN et al
Enzymatic or cofactor deficiencies can result in elevated homocysteine levels (hyperhomocysteinemia), which can have negative impacts systemically
In many chronic diseases, poor immunity and an increased rate of infections are linked to low GSH levels
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As a new form of cell death, it provides new research directions for the treatment and thinking of many diseases
The site includes Glu170 as well as candidate residues Gln143 (r 2 ) in helix 3, Arg152 (r 7 ) and Thr154-Pro156 in a loop preceding strand 3, and Gly167-Thr169 (r 46 ) in helix 4 (Figs 1c and 6a)
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