2011 Jun 27;11:50
GLP-1 therapy works synergistically with nutrition improvements, exercise, and behavioral changesthese combinations produce superior results than medication alone
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This is also why a secretagogue approach is framed as "axis-friendly": because endogenous somatostatin is still in the loop, negative feedback is preserved, which in principle restrains the supraphysiologic IGF-1 spikes seen with exogenous GH
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