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Oleanolic acid ( Figure 5 ), another triterpenoid structure, and its synthetic derivative SZC014 showed considerable antitumor effects against the hepatocellular cancer cell lines HepG2, interfering with NF-B and nuclear factor-erythroid factor 2-related factor 2 (Nrf-2)/antioxidant response element (ARE) signaling (233, 234)
This additional benefit further strengthens the cardioprotective profile of GLP-1 medications by addressing a key risk factor for CVD
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Curr Opin Lipidol 2012;23:334-44.ArticlePubMed 40
For most patients, the most effective longterm strategy after achieving a target weight is to continue GLP1 treatment
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