Overexpression of erythrocyte glutathione S-transferase in uremia and dialysis [PMID: 10508125] Laboratory literature summary: Overexpression of erythrocyte glutathione S-transferase in uremia and dialysis
The Phase 2 trial demonstrated that skipping steps or accelerating the titration nearly doubles the rate of gastrointestinal side effects
The Poisson model provided the best fit, highlighting a significant change in reporting trends after FDA approval
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These effects collectively contribute to improved glycaemic control
These effects tend to be dose-dependent, class-dependent, and are more frequent during the initial stages of treatment [114, 118]