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24 These growth factors induce proliferation of keratinocytes and fibroblasts, lead to new formation of capillaries in the granulation tissue, and modulate extracellular matrix deposition and reconstitution of the injured area

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Then, NAPQI-modified proteins were digested via two proteases (trypsin and pepsin) in parallel and analyzed by two-dimensional LC-MS/MS, using high-pH reversed-phase (RP) offline fractionation