Epithalon structure and discovery Chemical composition: Tetrapeptide (four amino acids) Sequence: Ala-Glu-Asp-Gly (AEDG) Also called Epitalon or Epithalone Synthetic version of epithalamin (pineal gland extract) Molecular weight: 390.35 g/mol Water-soluble peptide Discovery history: Discovered by Professor Vladimir Khavinson in St
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OBrien, A
Compound 5 was isolated by silica gel column chromatography using a dichloromethane/methanol (DCM:MeOH = 20:1, V/V) eluent (yield: 61%)
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