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8, 9, 10 Folate is primarily transported across the choroid plexus epithelium attached to the folate receptor (FR) using energy-dependent endocytosis (Supplementary Figure S1)
10.1111/bph.15472 39 FengK.LiX.BaiY.ZhangD.TianL
Still workable but tighter
These deleterious signaling cascades converge on mitochondria, where membrane-potential loss, electron-transport dysfunction, and mitochondrial permeability transition pore opening (mPTP) promote cytochrome c release and cell death [2,3,4,5,6,7,8]
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