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It is typically not recommended for patients with hepatic or renal impairment, uncontrolled hypertension, history of pancreatitis, or medullary thyroid cancer risk
In this form, it loses effectiveness
N Engl J Med 391:109121 Pratley RE, Tuttle KR, Rossing P (2024) Effects of Semaglutide on Heart Failure Outcomes in Diabetes and Chronic Kidney Disease in the FLOW Trial
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