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and c) irregular dietary patterns), reduced bioavailability (impairment of the intrinsic factor-mediated absorption pathway, often due to the widespread and prolonged use of proton pump inhibitors), and malabsorption syndromes

10.1016/0167-4943(90)90023-y 7 BurbaevaG.BokshaI.TereshkinaE

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These interactions may reduce the efficacy of drugs like oral contraceptives and alter the absorption of medications such as digoxin and statins, necessitating careful monitoring and adjustments

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