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These medications slow gastric emptying and reduce appetite, which can inadvertently decrease fluid intake while increasing the risk of dehydration through gastrointestinal symptoms like nausea, vomiting, and diarrhea

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Metformin has also been shown to promote weight loss and protect against some cancers, cardiovascular disease, and Alzheimer disease

Janus kinase/signal transducers and activator of transcription (JAK/STAT) and its role in Lung inflammatory disease