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Blocking NNMT raises intracellular NAD+ and SAM pools, theorized to drive lipolysis and improve insulin sensitivity in adipose tissue

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According to an article about cobalamin deficiency in Tufts Universitys catnip newsletter, people with cobalamin deficiency also experience changes with intestinal permeability and absorptive function

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The classic symptoms of B12 deficiency are persistent fatigue, tingling or numbness in the hands and feet, problems with memory and concentration, mouth ulcers, a sore red tongue, and pale or yellow-tinged skin

Detailed written and visual instructions are included with the B12 Self-Injection Kit