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Some start to feel dependent or even say they feel "addicted." But currently, there is no plan for how to get patients off GLP-1s

Uysal, H

Neuron 100(6):12921311 Echeverry S, Shi XQ, Yang M, Huang H, Wu Y, Lorenzo LE, Perez-Sanchez J, Bonin RP, De Koninck Y, Zhang J (2017) Spinal microglia are required for long-term maintenance of neuropathic pain

This means it acts on three hormone receptor pathways involved in appetite, fullness, blood sugar control and energy balance

( A ) Schematic of DART-Seq modification of the DROP-Seq nano bead

If even these alternatives dont strike your fancy, you could forgo supplements altogether and work on modifying your diet