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Presented for research literature review only Ozen H et al

Here we develop a series of peptides closely related to the GLP-1 homolog exendin-4, used clinically as exenatide 12 , but with widely varying trafficking properties

doi: 10.1111/bjh.19268 190 PaganiAVieillevoyeMNaiARausaMLadliMLacombeCet al

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Conclusion The metabolic market is too large for any serious pharmaceutical player to ignore, yet the barrier to entry is intentionally designed to be prohibitive