In the transgenic APPswePS1dE9 (APP/PS1) mouse model, which stimulates amyloidosis and gliosis, targeting reactive astrocytes improved cognitive function demonstrating their potential for treatment in AD 133
The potential for a clinic that combines GLP-1s with community, nutrition, and exercise is massive
Article updated 12/17/2025 to reflect recent FDA communications, regulatory clarifications and clinical context related to GLP-1 medications
Some people assume they can choose their additive the way they choose a supplement at a store
Bowel obstructions can be very serious, and they may require surgery
Cautions WARNING: RISK OF THYROID C-CELL TUMORS In both male and female rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures