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Data from the STEP 4 trial demonstrated that discontinuation of semaglutide typically results in return of appetite and substantial weight regain, indicating that for many individuals, ongoing treatment may be necessary to maintain benefits

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Coverage for compounded GLP-1 medications and telehealth weight management services varies significantly by insurer, plan, and state

Importantly, most side effects occur during dose escalation and tend to improve over time

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With retinol and retinoids , the issue is less about chemical destabilization and more about cumulative irritation and routine complexity