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In a head-to-head trial against semaglutide (the SURPASS-2 trial), tirzepatide produced significantly greater weight loss, with participants taking the highest dose of tirzepatide losing an average of 11.2 kg (24.7 lbs), compared to 5.7 kg (12.5 lbs) for those taking semaglutide 1 mg

Post-meal walks: 10 to 20 minutes of walking after lunch and dinner blunts the glucose and triglyceride spikes from meals, reducing the substrate that would otherwise be stored as visceral fat

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Its gastric stability makes it particularly suited for GI research, though human clinical evidence is currently absent

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