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In a Phase 2 of Phase 1/2 trial, patients on MET-097i showed a mean placebo-adjusted body weight of 11.3% after 12 weekly doses of 1.2 mg and 7.2% after 12 weekly doses of 0.6 mg

Finally, while available drugs address certain molecular targets and pathways, innovative MASH drugs modifying different pathways and targets remain to be investigated (Figure 1)

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New Insulin Delivery Recommendations. Mayo Clinic Proceedings , vol