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If anything, the EMA and WHO are being cautious by flagging a risk that is very low and is still not entirely certain in order to better inform the public
Bertelli PR, Mocelin R, Marcon M, Sachett A, Gomez R, Rosa AR, et al
Matuz-Mares D, Riveros-Rosas H, Vilchis-Landeros MM, Vzquez-Meza H
doi:10.1158/1940-6207.CAPR-19-0315
Compared to enzyme-cleavable linkers, chemically cleavable linkers offer more consistent performance across different patients and tissues, making them especially suitable for ADC designs requiring precise control of drug release rate and location, thereby improving therapeutic outcomes and lowering side effect risks
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