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Phase I detoxification involves the cytochrome P450 enzyme system, which breaks down fat-soluble toxinssuch as pharmaceutical medications, heavy metals, mold mycotoxins, and metabolic wasteinto intermediate compounds
This interaction leads to hypermethylation of the CDH1 (cadherin 1) promoter, resulting in the transcriptional silencing of CDH1 and the acceleration of epithelial mesenchymal transition (Xu et al., 2024)
No patient identifiers were included in the dataset used for this analysis
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Explain that healthful lifestyle changes must be made in concert with weight management medications
Equine Vet J Suppl
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